To test the functionality of specific genes relevant to heart,
lung and blood disorders, our initial screen of ENU mutant rats
will provide a broad assessment of a variety of cardiovascular
and pulmonary systems. All phenotypes will be measured in each
mutant rat under a variety of conditions. These include novel
and adapated environments for behavior phenotypes, low and high
salt diet conditions (strain specific) and fasting condition for
the biochemistry phenotypes.